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What Causes Diabetic Nerve Pain

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Peripheral Neuropathy Is When Diabetes Causes Damage To Your Nerves Particularly In Your Hands And Feet It Can Affect Different Types Of Nerves In Your Body Including In Your Feet Organs And Muscles

Nerves carry messages between the brain and every part of our bodies so that we can see, hear, feel and move. They also carry signals to parts of the body such as the heart, making it beat at different speeds, and the lungs, so we can breathe. 

Damage to the nerves can therefore cause serious problems in various parts of the body for people with type 1, type 2 or other types of diabetes. Common symptoms can include leg pain, muscle weakness or numbness and tingling in your feet or hands.? 

Treatments For Gastrointestinal Problems Caused By Diabetic Neuropathies

Eating small and frequent meals that are low in fat and fiber may help relieve symptoms such as belching, indigestion, flatulence, nausea or vomiting caused by damage to the nerves supplying the gastrointestinal tract.

Medications such as erythromycin and metoclopramide may help speed the passage of food through the gastrointestinal tract and metoclopramide can also help relieve nausea. Other medications may be prescribed to reduce stomach acid secretion or control diarrhea.

I Have Diabetes And Im Worried About Neuropathy Pain What Should I Do

If you have diabetes and are concerned about diabetes nerve pain, contact your doctor or health care professional immediately to discuss your symptoms or take their advice.

Doctors can diagnose diabetic nerve pain and also help educate those with diabetes to manage blood sugar levels more effectively.

Clinical Phenotype Of Distal Symmetric Peripheral Neuropathy

Peripheral neuropathy is a broad term that refers to damage to various components of the peripheral nerve, extending from the cell body to the cell projection itself, with its myelin outer coating and axonal projection. Peripheral neuropathy can involve motor, sensory or autonomic fibers depending on the underlying cause. Diabetes is associated with a wide spectrum of peripheral nerve complications. The most common are distal symmetric polyneuropathy and autonomic neuropathy.

DPN causes a length?dependent ‘stocking‘ or ‘stocking glove‘ pattern of sensory loss. DPN can affect large?diameter myelinated A?beta somatic fibers , which are responsible for joint position, vibration and touch/protective sensation. Clinically, patients whose neuropathy affects large fibers complain of numbness, tingling and often aching discomfort. Gait instability is common, particularly when walking in the dark or on uneven ground. Most patients with DPN have large fiber involvement, particularly those with longstanding neuropathy. Large fiber neuropathy can lead to loss of protective sensation in the absence of sensory symptoms, placing the patient at significant risk of ulceration and ultimately amputation. Nerve conduction studies are commonly used to evaluate large fiber neuropathy.

Autonomic Neuropathy: Gastrointestinal And Urinary Symptoms

Diabetic Neuropathy: Causes, Types, and Natural Relief ...

Our gastrointestinal tract is also under the control of the autonomic nervous system. Constipation is typically the first sign that the nerves that supply the GI tract have been damaged. Gastroparesis – a condition characterized by a significant slowing of the muscle contractions of the stomach – can also occur, leading to persistent nausea and vomiting, bloating and a loss of appetite. People may also experience weight loss, diarrhea, and difficulty swallowing.

Recurrent urinary tract infections may be a sign of damage to the nerves that control urination and sexual function. Bacteria are more likely to grow in urine that is allowed to sit for long periods of time in people unable to empty their bladders completely. Urinary incontinence and erectile dysfunction typically occur in people with autonomic neuropathy of the genitourinary tract.

Antibiotics may be needed to clear up a UTI, and scheduling urination at regular intervals may reduce bladder ‘accidents’. Further investigations may be needed to determine other contributing causes of ED before prescribing oral medications, or other, more suitable treatments.

What Does Diabetic Nerve Pain Feel Like 11 Common Symptoms

Diabetes is a complex chronic condition that comes with a host of symptoms if not properly managed. One of the most complicated and challenging symptoms to treat is diabetic peripheral neuropathy. Also referred to a peripheral neuropathy or diabetic foot pain, this complicated condition requires thoughtful diagnosis and comprehensive treatment. What is peripheral neuropathy, and what does diabetic nerve pain feel like? Here’s what you need to know.

Diabetes And Your Feet: How To Prevent And Treat Foot Pain

Christina Aungst, PharmD

Diabetes-related foot pain is a common complication that happens to many people with diabetes. It happens to those with both type 1 and type 2 diabetes. The longer you have diabetes and the less controlled your blood sugar is, the more likely it is you will develop foot pain or discomfort at some point.

Control Your Diabetic Neuropathy With Ethos Health Group

The best thing you can do to slow the progression of diabetic neuropathy is to see a specialist and devise a care plan. 

Along with your doctor, you and your specialist can manage your symptoms and reduce your pain to get back to enjoying your life. 

When you visit Ethos Health Group, we’ll perform a series of non-invasive tests that tell us just how much your diabetic neuropathy has progressed.

This will let us know what options exist for you. 

The treatment programs at Ethos Health Group consist of cutting-edge, non-invasive therapies designed to stimulate new blood vessels’ growth to help reverse nerve damage in the feet or hands. 

If you’re ready to find relief from your diabetic neuropathy, you should contact Ethos Health Group as soon as possible.

What Causes Neuropathy A Deeper Look Into The Condition

It is believed that nearly 20 million people in this country suffer from neuropathy. As a result, the condition is being extensively studied in an effort to determine its causes. After all, if the causes can be fully identified, there is a better chance of developing a successful way of treating it.

In this particular condition, there has been some sort of damage to the way the central nervous system communicates with the rest of the body. As a result, people can experience a range of symptoms, including muscle weakness, paresthesia , tingling, and numbness.

It is also common for particular areas of the body to be more significantly affected, with some even developing allodynia, which is an intense reaction to touch. Symptoms tend to be worst at night, when gland or organ dysfunction, paralysis, muscle wasting, and burning pain can occur. Over time, people may experience organ failure, breathing difficulties, and damage to the urinary tract, sexual organs, and digestive system.

What Is The Outlook For People With Diabetic Neuropathy

Although reversing nerve damage is difficult, you can still live a high quality of life. Your healthcare provider may prescribe medications to keep pain at bay.

Lifestyle adjustments can be effective, such as:

  • Using a cane to help you move easier.
  • Wearing special shoes to try to protect feet from injuries and skin breakdown.
  • Getting help from a wound clinic to treat and heal foot and leg wounds.
  • Removing throw rugs and other tripping hazards to prevent falls.

What Is Diabetic Nerve Pain Symptoms Causes Treatments

Diabetic nerve pain is nerve damage, or neuropathy, that can occur in people living with diabetes. There are four different types of diabetic neuropathy:

  • peripheral
  • autonomic
  • radiculoplexus
  • mononeuropathy
  • Diabetic nerve pain symptoms and experiences vary according to type. People can experience just one type or more than one.

    Consequences of nerve damage in diabetes can be dire. People might experience physical and emotional pain that lead to diminished quality of life, mental health problems such as anxiety and depression, and increased mortality rates compared to those without diabetic nerve pain . Given that almost 45 percent of people living with diabetes develop at least one type of neuropathy , understanding the symptoms, causes, and treatments is crucial.

    Stop Smoking And Limit Or Avoid Consumption Of Alcohol

    Health begins with what you put in your body. Tobacco products in any form inhibit the body’s healing response and narrow already challenged blood vessels. Alcohol has a similar effect on the immune system, dampening the body’s response to infection.

    Some people are able to consume a daily glass of red wine or two, but talk to your doctor. In acute stages of infection, avoid alcohol.

    How Can People Prevent And Manage Diabetic Neuropathy

    The Source of Diabetic Nerve Pain Finally Revealed ...

    Managing diabetes and keeping blood sugar under control is key to reducing a person’s risk of developing diabetic neuropathy.

    Once diabetic neuropathy develops, it is not reversible. However, taking steps to manage diabetes may help stop neuropathy from worsening.

    “If I have a patient who has diabetes, the most important thing is to get it under control,” said Dr. Rosenberg. “If a person’s diabetes is under control, that’s the best chance to keep diabetic neuropathy from getting worse.”

    Some treatments may help ease symptoms of diabetic neuropathy and reduce the risks of associated complications.

    How Does Neuropathic Pain Affect People With Diabetes

    Diabetic nerve pain unfortunately can be very dangerous for people with diabetes.

    At an early stage it can impact on day to day activities such as walking, exercising or working with the hands.

    At a later stage diabetic nerve pain can make even standing difficult.

    One of the dangers of diabetic neuropathy is if it leads to a foot ulcer developing as high blood sugars and poor circulation can both mean the wound may take longer to heal and be more susceptible to infection getting in, which can sometime result in amputation.

    What Are The Best Medications For Diabetic Neuropathy

    The pain of diabetic neuropathy can sometimes be managed with certain medications. Certain prescription antidepressants and antiseizure medications have been shown to be effective in relieving pain that originates in the nerves.

    For example:

    In severe cases, opioid analgesic medications may be needed.

    Other kinds of treatment for nerve pain include patches containing the topical anesthetic agent lidocaine. Capsaicin cream is an over-the-counter topical agent that has been shown to relieve nerve pain.

    Medications can also help manage the troublesome symptoms of autonomic neuropathy. For example, antispasmodic or anticholinergic drugs can help prevent urinary incontinence. Drugs to treat erectile dysfunction like sildenafil , tadalafil , and vardenafil may help some men with ED due to diabetic neuropathy. For women, vaginal estrogen creams and lubricants may provide relief of vaginal dryness and irritation.

    Botulinum toxin injections have been used to treat abnormal sweating.

    Life Expectancy Of Someone With Diabetic Neuropathy

    Diabetic autonomic neuropathy may lead to a silent myocardial infarction, which is a condition of the heart. This can lead to the death of almost 25 percent to 50 percent of people suffering from diabetic neuropathy, within a period as short as 5 to 10 years.

    According to some studies, almost 2/3rd of the diabetic patients all over, suffer from diabetic neuropathy. of all the people suffering from diabetes of different types- insulin-dependent diabetes mellitus, non-insulin dependent diabetes mellitus, secondary diabetes; anyone can develop diabetic neuropathy. the longer the person is suffering from diabetes mellitus, the higher are the chances of developing diabetic neuropathy.

    What Is Diabetic Nerve Pain Or Diabetic Neuropathy

    Neuropathy is an over-arching term that means nerve pain. There are four types of neuropathy, including:

    • Peripheral neuropathy
    • Radiculoplexus neuropathy
    • Mononeuropathy

    Peripheral neuropathy refers to nerve pain that is experienced on the periphery of your body, like the hands and feet. This area is enervated by the peripheral nervous system .

    There are many conditions that can result in nerve pain in the farthest reaches of the body, including:

    • Vitamin deficiencies
    • Certain medications

    The most common cause of peripheral neuropathy, though, is poorly controlled diabetes.

    The hallmark of diabetes is a nearly constant fluctuation of the blood sugar, with spiky highs and cavernous lows. This constant fluctuation damages the capillary walls responsible for delivering blood to the nerves, especially in the hands and feet. As the capillaries become more damaged, diabetic neuropathy symptoms begin to appear.

    The Many Factors That Lead To Diabetic Nerve Pain

    Sari Harrar

    Diabetic peripheral neuropathy—DPN for short—is diabetes-related damage to nerves that sit near the surface of your skin. DPN usually affects the feet and the hands but can also harm nerves in arms and legs.

    Approximately 50 percent of people with type 2 diabetes and 20% of those with type 1 diabetes develop this kind of nerve damage.1  DPN can be extremely painful—or cause numbness so that you have little feeling, especially in your feet.

    Diabetic neuropathy occurs in two different types of nerves close to the surface of your skin. DPN can affect small nerves that protect your body by sending signals about pain and temperature changes to your brain. This condition can also attack large nerves that detect touch, pressure and help you keep your balance.2 Symptoms are different for each type of neuropathy but most people with DPN have damage that occurs to both types of nerves.

    This diabetes-related complication usually affects extremities—feet, hands, legs and arms—where nerve fibers are the longest and most numerous.2

    Causes Experts are still investigating exactly how diabetes harms and kills these nerve cells. “The causes remain unknown,”1 according to findings shared in a position paper issued by the American Diabetes Association .

    The major threats are:

    However, the nerves get damaged, the end result is the same: they aren’t able to convey messages as well as they should to the brain, and they lose their ability to help you feel and move.

    What Are The Complications Of Diabetic Neuropathy

    Peripheral neuropathy can challenge your balance. Nerve pain may make it hard to walk or even sit still comfortably. Nerve damage may mean you don’t notice foot injury right away.

    For people with diabetes, foot and leg wounds need treatment right away. Diabetes can cause or worsen problems such as peripheral artery disease . Without treatment, PAD can lead to amputations.

    How Can I Best Learn To Cope With Neuropathy Pain

    People with nerve damage may get depressed or discouraged. Talk with your healthcare provider about your mental health. You may benefit from:

    • Joining a support group to connect with others.
    • Practicing destressing techniques, such as meditation or breathing exercises.
    • Starting therapy.
    • Taking medications such as antidepressants, which can reduce pain.

    A note from Cleveland Clinic

    Diabetic neuropathy is nerve damage caused by elevated blood sugar. You are more likely to develop diabetic neuropathy if you have diabetes that is not well-managed. Smoking, excessive drinking and high blood pressure are also risk factors. If you have diabetic neuropathy, your healthcare provider may prescribe pain medications. You also need to manage your blood sugar with proper nutrition and exercise. Many people with nerve damage may feel depressed or discouraged. Talk with your healthcare provider about your mental health. You may consider starting therapy or joining a support group for people with diabetic nerve damage.

    Last reviewed by a Cleveland Clinic medical professional on 04/29/2021.

    References

    Peripheral Neuropathy: Should Be Taken Seriously

    Does Diabetic Nerve Pain Cause Swelling

    Peripheral neuropathy is the most common type of diabetic nerve pain. The feet and legs are usually the first to be affected, but with time, the hands and arms may also show signs. Symptoms include:

    • Numbness or an inability to distinguish between different temperatures
    • Pins and needles, tingling, or burning sensation in the affected areas
    • Cramps or sharp pains
    • An extreme sensitivity to even the lightest touch
    • Coordination or balance problems.

    Because the condition happens gradually over time, your doctor may pick up on signs or symptoms of peripheral neuropathy before you do. Left unmanaged, the condition may affect the muscles, causing weakness and a loss of reflexes. Eventually, this may affect your ability to walk.

    One of the biggest concerns with peripheral neuropathy is the lack of awareness of injury to the foot. Any break in the tissue caused by sharp toenails, tight-fitting shoes, or as a result of trauma, becomes a potential entry point for bacteria and there is a high risk of an infection spreading to the bone. Diabetes is a leading cause of lower limb amputation. Recognizing and treating minor foot problems early in people with peripheral neuropathy is the best way of preventing amputations.

    What Kind Of Doctor Treats Peripheral Neuropathy

    Neurologists treat neuropathy.

    A diabetic specialist will prescribe pain medications and other treatments to help you manage your diabetic symptoms.

    Specialists can prescribe pain medications and other treatments to help you manage your diabetic symptoms.

    Some diabetic specialists may recommend non-steroidal anti-inflammatory drugs like ibuprofen for pain relief, which can be taken as needed or on a regular basis.

    Diabetic neuropathies cannot be cured but they can be managed by using various diabetes treatment options available including medication and physical therapies.

    It’s important to be aware of diabetic neuropathy so you can manage it properly and take the necessary precautions.

    Natural Diabetic Neuropathy Treatments That Work

    March 7, 2016

    Diabetes itself is extremely common, affecting about one in every three adults in the U.S., and diabetic neuropathy is one of the most likely complications to develop as a side effect because high blood sugar levels affect nerve fibers throughout the body. Neuropathy is a pathological condition that encompasses more than 100 different forms and manifestations of nerve damage, both in people with diabetes and those without.

    Diabetic neuropathy is the term for nerve damage caused by diabetes, a chronic condition that occurs when the body doesn’t use the hormone insulin properly. Neuropathy can form anywhere but is most likely to affect nerves running through the limbs, hands and feet.

    Not every person with diabetes symptoms develops complications such as neuropathy, but many do. In fact, up to 60 percent to 70 percent of all diabetics experience some form of neuropathy. For some people, only mild symptoms develop from nerve damage, such as tingling or numbness in the limbs. But for others, neuropathy causes a good amount of pain, digestive issues, problems with the heart and blood vessels, the inability to go about life normally, and even death if major organs are affected badly enough.

    Can You Have Neuropathy Without Having Diabetes

    Neuropathy Program

    Answering this question is quite easy.

    Yes, you can have neuropathy without having diabetes. In fact, the list of potential causes is very long. Diabetes is the most common cause, however, because it can cause serious damage to the nerves in the body’s extremities, especially the feet and hands. In fact, the condition many people talk about is called peripheral neuropathy.

    The word “peripheral” refers to the edges of the body, such as feet, lower legs, hands and wrists. Diabetes is one cause, along with alcoholism, deficiency in vitamin B12, thyroid problems, protein disorders, kidney disease, rheumatoid arthritis, poisoning from heavy metals or other toxins, diseases of the autoimmune system etc.

    How Does Diabetes Affect The Health Of My Feet

    Diabetes-related foot pain is mainly caused by high blood sugar levels. Over time, high levels of sugar in the blood damage both the nerve endings and blood vessels throughout the body. This combination causes nerve pain and poor circulation. 

    The feet are especially prone to poor circulation because they’re so far away from the heart. Diabetes-related nerve pain can appear in the hands, but most people who experience it feel it in their feet first. 

    Other factors that can increase your risk of developing diabetes-related foot pain include being overweight, kidney disease, and smoking.

    Epidemiology Linking Prediabetes Mets And Cspn

    Parallel literature shows that patients with CSPN have an increased risk for prediabetes. This observation was first brought to attention by clinicians caring for patients with CSPN who observed that patients who did not have diabetes shared many phenotypic characteristics including obesity, hypertension and dyslipidemia. Several studies have shown that patients with CSPN are at higher risk of having IGT and/or MetS. Up to 40–50% of CSPN patients have prediabetes, . In one study, 73 patients with confirmed CSPN were subjected to an oral glucose tolerance test; 41 had abnormal glucose metabolism, 15 of whom had diabetes and 26 of whom had IGT. Those with IGT had predominantly small fiber involvement, whereas diabetes patients had large fiber involvement.

    Who Is Most Likely To Get Diabetic Neuropathy

    If you have diabetes, your chance of developing nerve damage caused by diabetes increases the older you get and the longer you have diabetes. Managing your diabetes is an important part of preventing health problems such as diabetic neuropathy.

    You are also more likely to develop nerve damage if you have diabetes and

    • are overweight

    Research also suggests that certain genes may make people more likely to develop diabetic neuropathy.

    Autonomic Neuropathy: Outside Of Our Control

    Many muscles and organs inside our body are not under our conscious control. The nerves that control them form part of the autonomic nervous system and autonomic neuropathy is a diabetic nerve disorder that occurs when the nerves that supply these involuntary muscles are damaged.

    Symptoms of autonomic neuropathy reflect the part of the body that is affected; several areas may be affected at once. Symptoms may include:

    • Dizziness or fainting when going from a lying or sitting position to standing. This reflects damage to the nerves in the cardiovascular system making it difficult for the body to adjust blood pressure in response to changes in body position.
    • A lack of awareness of hypoglycemia . Most diabetics feel shaky, sweat or develop heart palpitations when their blood sugar levels drop below 70 mg/dL. These symptoms may not occur in people with autonomic neuropathy.

    Association Of Vascular Risk Factors With Dn

    Diabetic Neuropathy : Symptoms, Treatment and Medicines ...

    The risk factors for development of DSPN in 1172 patients with type I DM was studied over 7.3 years. Clinical evaluation, quantitative sensory testing, autonomic function tests, serum lipids and lipoprotein, glycosylated Hb, urinary albumin excretion rate, and serum creatinine were measured in 276 patients. In this study 23.5% developed neuropathy, which apart from the glycaemic control was related to potentially modifiable cardiovascular risk factors including raised serum triglyceride, body mass index, smoking, and hypertension. A stepwise progressive study of treatment of type II diabetic patients with hypotensive drugs, angiotensin converting enzyme inhibitors, calcium channel blockers, hypoglycaemic agents, aspirin, hypolipidaemic agents, and antioxidants. This study argues for the multifactorial nature of neuropathy and need for managing multiple metabolic abnormalities.

    What Are The Symptoms Of Diabetic Neuropathy

    Your symptoms depend on which type of diabetic neuropathy you have. In peripheral neuropathy, some people may have a loss of sensation in their feet, while others may have burning or shooting pain in their lower legs. Most nerve damage develops over many years, and some people may not notice symptoms of mild nerve damage for a long time. In some people, severe pain begins suddenly.

    What Problems Does Diabetic Neuropathy Cause

    Peripheral neuropathy can lead to foot complications, such as sores, ulcers, and infections, because nerve damage can make you lose feeling in your feet. As a result, you may not notice that your shoes are causing a sore or that you have injured your feet. Nerve damage can also cause problems with balance and coordination, leading to falls and fractures.

    These problems may make it difficult for you to get around easily, causing you to lose some of your independence. In some people with diabetes, nerve damage causes chronic pain, which can lead to anxiety and depression.

    Autonomic neuropathy can cause problems with how your organs work, including problems with your heart rate and blood pressure, digestion, urination, and ability to sense when you have low blood glucose.

    Diagnostic Criteria For Prediabetes And Mets

    Prediabetes represents the earliest stage of glucose dysregulation, and precedes the development of overt type 2 diabetes. Prediabetes can be divided into impaired fasting glucose or impaired glucose tolerance . The American Diabetes Association defines prediabetes as a hemoglobin A1c of 5.7–6.4%. Prediabetes can be separated into IFG and IGT using a 2?h oral glucose tolerance test . After measurement of a fasting plasma glucose early in the morning , the patient is given 75 g of oral anhydrous dextrose, and the glucose is repeated 2 h later. A fasting plasma glucose of 100–125 mg/dL defines IFG, and a 2?h oral glucose of 140–199 mg/dL defines IGT. The diagnosis of diabetes requires a hemoglobin A1c of >6.5%, a fasting glucose >126 mg/dL or a 2?h glucose of >200 mg/dL . It is worth noting, nevertheless, that the 2?h OGTT has been noted to have reduced reproducibility in diagnosing patients with IGT as compared with diabetes patients and normoglycemic patients . Repeat testing should be considered to confirm the diagnosis. The prevalence of IFG and IGT varies internationally by ethnicity, with IFG being generally more common among men. It is expected that up to 472 million adults worldwide will have IGT by 2030, with the greatest anticipated rise in southeast Asia and the western Pacific.


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